diff --git a/dynamic-layers/clang-layer/recipes-core/ispc/ispc_1.17.0.bb b/dynamic-layers/clang-layer/recipes-core/ispc/ispc_1.17.0.bb
index fa03a3d0..cfd8e5bc 100644
--- a/dynamic-layers/clang-layer/recipes-core/ispc/ispc_1.17.0.bb
+++ b/dynamic-layers/clang-layer/recipes-core/ispc/ispc_1.17.0.bb
@@ -29,6 +29,11 @@ EXTRA_OECMAKE += " \
                   -DISPC_NO_DUMPS=ON  \
                   -DARM_ENABLED=OFF  \
                   -DISPC_CROSS=ON  \
+                  -DISPC_ANDROID_TARGET=OFF  \
+                  -DISPC_FREEBSD_TARGET=OFF  \
+                  -DISPC_WINDOWS_TARGET=OFF  \
+                  -DISPC_IOS_TARGET=OFF  \
+                  -DISPC_PS4_TARGET=OFF  \
                   -DSYSROOT_DIR=${STAGING_DIR_NATIVE}  \
                   "