diff --git a/meta/recipes-graphics/mesa/files/0001-rusticl-provide-cross-compilation-arguments-to-LLVM-.patch b/meta/recipes-graphics/mesa/files/0001-rusticl-provide-cross-compilation-arguments-to-LLVM-.patch
new file mode 100644
index 0000000000..d527b34087
--- /dev/null
+++ b/meta/recipes-graphics/mesa/files/0001-rusticl-provide-cross-compilation-arguments-to-LLVM-.patch
@@ -0,0 +1,67 @@
+From b9cf34f39ca7e7546508ce2ab1f053edef5fc201 Mon Sep 17 00:00:00 2001
+From: Dmitry Baryshkov <dmitry.baryshkov@oss.qualcomm.com>
+Date: Wed, 26 Mar 2025 17:47:09 +0200
+Subject: [PATCH] rusticl: provide cross-compilation arguments to LLVM bindgen
+ invocation
+
+Correctly generating LLVM bindings requires several croos-compilation
+arguments. Provide them to rust.bindgen(). Karol Herbst on IRC suggested
+that a proper fix should be to fix meson's rust.bindgen() to support
+cross-compilation. Carry this patch until meson is fixed.
+
+Upstream-Status: Inappropriate [OE-Specific]
+Link: https://github.com/mesonbuild/meson/issues/13591
+Signed-off-by: Dmitry Baryshkov <dmitry.baryshkov@oss.qualcomm.com>
+---
+ meson_options.txt                         | 14 ++++++++++++++
+ src/gallium/frontends/rusticl/meson.build |  8 ++++++++
+ 2 files changed, 22 insertions(+)
+
+diff --git a/meson_options.txt b/meson_options.txt
+index 0147cafcb146..f73e83fded18 100644
+--- a/meson_options.txt
++++ b/meson_options.txt
+@@ -796,3 +796,17 @@ option(
+   value : false,
+   description : 'Install the drivers internal shader compilers (if needed for cross builds).'
+ )
++
++option(
++  'bindgen-includedir',
++  type : 'string',
++  value : '',
++  description : 'system-wide include directory for cross-generating LLVM bindings'
++  )
++
++option(
++  'bindgen-target',
++  type : 'string',
++  value : '',
++  description : 'Clang target for cross-generating LLVM bindings'
++  )
+diff --git a/src/gallium/frontends/rusticl/meson.build b/src/gallium/frontends/rusticl/meson.build
+index a5d1dcf3abb9..480c220b7f5f 100644
+--- a/src/gallium/frontends/rusticl/meson.build
++++ b/src/gallium/frontends/rusticl/meson.build
+@@ -115,6 +115,11 @@ rusticl_bindgen_c_args = [
+   '-fno-builtin-malloc',
+ ]
+ 
++bindgen_target = get_option('bindgen-target')
++if bindgen_target != ''
++  rusticl_bindgen_c_args += [ '-target', bindgen_target ]
++endif
++
+ cl_c_args = [
+   '-DCL_USE_DEPRECATED_OPENCL_1_0_APIS',
+   '-DCL_USE_DEPRECATED_OPENCL_1_1_APIS',
+@@ -187,6 +192,9 @@ rusticl_llvm_bindings_rs = rust.bindgen(
+     rusticl_bindgen_c_args,
+     pre_args,
+   ],
++  include_directories : [
++    get_option('bindgen-includedir'),
++  ],
+   dependencies : [
+     dep_clang,
+     dep_llvm,
diff --git a/meta/recipes-graphics/mesa/mesa.inc b/meta/recipes-graphics/mesa/mesa.inc
index 9edce6b228..aca34983e9 100644
--- a/meta/recipes-graphics/mesa/mesa.inc
+++ b/meta/recipes-graphics/mesa/mesa.inc
@@ -18,6 +18,7 @@ SRC_URI = "https://archive.mesa3d.org/mesa-${PV}.tar.xz \
            file://0001-meson-misdetects-64bit-atomics-on-mips-clang.patch \
            file://0001-meson-disable-SIMD-blake-optimisations-on-x32-host.patch \
            file://0001-freedreno-don-t-encode-build-path-into-binaries.patch\
+           file://0001-rusticl-provide-cross-compilation-arguments-to-LLVM-.patch \
 "
 
 SRC_URI[sha256sum] = "adf904d083b308df95898600ffed435f4b5c600d95fb6ec6d4c45638627fdc97"
@@ -46,7 +47,7 @@ PROVIDES = " \
     virtual/mesa \
     "
 
-inherit meson pkgconfig python3native gettext features_check
+inherit meson pkgconfig python3native gettext features_check rust
 
 BBCLASSEXTEND = "native nativesdk"
 
@@ -85,6 +86,9 @@ PACKAGECONFIG = " \
 	${@bb.utils.contains('DISTRO_FEATURES', 'vulkan', 'zink', '', d)} \
 "
 
+# skip all Rust dependencies if we are not building OpenCL"
+INHIBIT_DEFAULT_RUST_DEPS = "${@bb.utils.contains('PACKAGECONFIG', 'opencl', '', '1', d)}"
+
 PACKAGECONFIG:append:x86 = " libclc gallium-llvm"
 PACKAGECONFIG:append:x86-64 = " libclc gallium-llvm"
 PACKAGECONFIG:append:i686 = " libclc gallium-llvm"
@@ -144,9 +148,16 @@ PACKAGECONFIG[gles] = "-Dgles1=enabled -Dgles2=enabled, -Dgles1=disabled -Dgles2
 # "egl" requires "opengl"
 PACKAGECONFIG[egl] = "-Degl=enabled, -Degl=disabled"
 
+BINDGEN_TARGET = "${TARGET_ARCH}-${TARGET_OS}${@['-gnu', ''][d.getVar('LIBCEXTENSION') != '']}"
+BINDGEN_TARGET:class-native = ""
+
 # "opencl" also requires libclc and gallium-llvm to be present in PKGCONFIG!
 # Be sure to enable them both for the target and for the native build.
-PACKAGECONFIG[opencl] = "-Dgallium-opencl=icd,-Dgallium-opencl=disabled,"
+PACKAGECONFIG[opencl] = " \
+    -Dgallium-opencl=icd -Dgallium-rusticl=true -Dbindgen-includedir=${STAGING_INCDIR} -Dbindgen-target=${BINDGEN_TARGET},\
+    -Dgallium-opencl=disabled -Dgallium-rusticl=false, \
+    bindgen-cli-native \
+"
 
 PACKAGECONFIG[broadcom] = ""
 PACKAGECONFIG[etnaviv] = ",,python3-pycparser-native"
@@ -249,7 +260,7 @@ RDEPENDS:libgles3-mesa-dev += "libgles2-mesa-dev"
 RDEPENDS:libgles2-mesa += "libgles3-mesa"
 ALLOW_EMPTY:libgles3-mesa = "1"
 
-RDEPENDS:libopencl-mesa += "${@bb.utils.contains('PACKAGECONFIG', 'opencl', 'libclc spirv-tools', '', d)}"
+RDEPENDS:libopencl-mesa += "${@bb.utils.contains('PACKAGECONFIG', 'opencl', 'libclc spirv-tools spirv-llvm-translator', '', d)}"
 
 PACKAGES =+ "libegl-mesa libegl-mesa-dev \
              libosmesa libosmesa-dev \
@@ -355,7 +366,7 @@ FILES:libgles1-mesa = "${libdir}/libGLESv1*.so.*"
 FILES:libgles2-mesa = "${libdir}/libGLESv2.so.*"
 FILES:libgl-mesa = "${libdir}/libGL.so.*"
 FILES:libglx-mesa = "${libdir}/libGLX*.so.*"
-FILES:libopencl-mesa = "${libdir}/libMesaOpenCL.so.* ${libdir}/gallium-pipe/*.so ${sysconfdir}/OpenCL/vendors/mesa.icd"
+FILES:libopencl-mesa = "${libdir}/lib*OpenCL.so.* ${libdir}/gallium-pipe/*.so ${sysconfdir}/OpenCL/vendors/*.icd"
 FILES:libglapi = "${libdir}/libglapi.so.*"
 FILES:libosmesa = "${libdir}/libOSMesa.so.*"
 FILES:libxatracker = "${libdir}/libxatracker.so.*"
@@ -369,7 +380,7 @@ FILES:libglapi-dev = "${libdir}/libglapi.*"
 FILES:libgles1-mesa-dev = "${libdir}/libGLESv1*.* ${includedir}/GLES ${libdir}/pkgconfig/glesv1*.pc"
 FILES:libgles2-mesa-dev = "${libdir}/libGLESv2.* ${includedir}/GLES2 ${libdir}/pkgconfig/glesv2.pc"
 FILES:libgles3-mesa-dev = "${includedir}/GLES3"
-FILES:libopencl-mesa-dev = "${libdir}/libMesaOpenCL.so"
+FILES:libopencl-mesa-dev = "${libdir}/lib*OpenCL.so"
 FILES:libosmesa-dev = "${libdir}/libOSMesa.* ${includedir}/GL/osmesa.h ${libdir}/pkgconfig/osmesa.pc"
 FILES:libxatracker-dev = "${libdir}/libxatracker.so ${libdir}/libxatracker.la \
                           ${includedir}/xa_tracker.h ${includedir}/xa_composite.h ${includedir}/xa_context.h \